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• W2387741991 abstract "Aim:To study the value of detecting serum cystatin C(Cys-C) in early diagnosis of contrast induced nephropathy(CIN).Methods:Taking retrospective analysis method,a total of 427 patients undergoing diagnostic coronary angiography or percutaneous coronary intervention were enrolled.Serum Cys-C,serum creatinine(Scr) and other relevant clinical data of the patients were collected before imaging and 24 hours,48 hours after imaging.Two methods were used to diagnose CIN.A:detecting the level of Scr;B:detecting the level of serum Cys-C.The specificity and sensitivity of the above two methods were analyzed respectively.Results:Compared with that before imaging[(1.03±0.18)mg/L],the serum Cys-C increased significantly at 24 hours[(1.27±0.21)mg/L] and 48 hours[(1.31±0.26)mg/L] after imaging(F=39.542,P=0.031).By method A,the incidence of CIN were 6.57% at 24 hours after imaging and 7.20% at 48 hours after imaging,which were lower than those by method B(10.17% and 10.81%,χ2=262.359 and 236.669,P0.001).By method B,the specificity and sensitivity of diagnosing CIN were 96.77% and 95.92% at 24 hours after imaging,91.18% and 95.43% at 48 hours after imaging.Conclusion:The level of serum Cys-C could be a sensitive marker to diagnose CIN in early stage." @default.
• W2387741991 created "2016-06-24" @default.
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• W2387741991 date "2012-01-01" @default.
• W2387741991 modified "2023-09-23" @default.
• W2387741991 title "Value of serum cystatin C in early diagnosis of contrast induced nephropathy" @default.
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