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- W2387755138 abstract "Objective To investigate the capability of surgically removing skull base tumor with cavernous sinus invasion, the indications and the key point of the operation. Methods Through transmaxillary, subfrontal-orbital, or preauricular subtemporal-infratemporal approach, 32 consecutive cases of skull base tumor with cavernous sinus invasion were removed safely from the bottom of the skull base in China-Japan Friendship Hospital and Cancer Hospital during November of 1998 and May of 2002. The clinical data were reviewed. Results The patients involved in this group were 7 angiofibroma, 5 chordoma, 5 nasopharyngeal carcinoma or cystic adenocarcinoma, 5 nasal sinus carcinoma, 3 Schwannoma, 1 olfactory epithelioblastoma, and 6 poor differentiated carcinoma or sarcoma. The tumors could be totally removed in all cases under surgical microscope. There were no perioperative mortality and morbidity. Most of the cases had to sacrifice one or more involved cranial nerves, but the internal carotid artery (ICA) could be saved in 31/32 patients. Of the 17 cases with malignant tumor, the entire cavernous sinus with cranial nerves and ICA were removed only in one case. Since we could not get enough safe border on the site of the cavernous sinus, postoperative radiation therapy was given for those patients with malignant tumor. The follow up period are 3-50 months in 29 patients with mean period of 19 months. Of these 29 patients, 4 died of tumor recurrence in 3-6 months after operation, 4 live with recurrent tumor 7-24 months after operation, 21 patients are tumor free at last follow up and back to there routine life. Conclusions The skull base tumor with cavernous sinus invasion could be removed successfully through various approaches. For this kind of tumors, dissecting cavernous sinus could be done more easily from its bottom than from intracranial. The exposure is wide and satisfactory . The lesion as well as the important anatomy structures can be viewed directly and clearly. The close cooperation between neurosurgeon and head and neck surgeon is one of the key points for this kind of difficult operation." @default.
- W2387755138 created "2016-06-24" @default.
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- W2387755138 date "2005-01-01" @default.
- W2387755138 modified "2023-09-26" @default.
- W2387755138 title "Surgical removal of the skull base tumor with cavernous sinus invasion" @default.
- W2387755138 hasPublicationYear "2005" @default.
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