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- W2387757924 abstract "The objective of this study was to evaluate the efficacy and toxicity of irinotecan plus capecitabine(XELIRI regimen)compared with irinotecan plus 5-FU/LV(FOLFIRI regimen)in the treatment of advanced colorectal cancer.From July 8.2006 to April 5.2008,data of 30 patients with advanced colorectal cancer treated with XELIRI regimen was retrospectively analysed and compared with 32 patients treated with FOLFIRI regimen,to evaluate the efficacy and toxicity beteween them.The overall response rate of the XELIRI regimen and the FOLFIRI regimen were 33.3% and 34.4% respectively,response rate of the 0riginal chemotherapy and second-line chemotherapy beteween the two regimens had no statistically significant difference.In the adverse effects of treatment,The most common grade 3 to 4 toxicities of XELIRI regimen were diarrhea and hand-foot syndrome,and neutropenia in FOLFIRI regimen,but there were no death during the treatment,all in the range of tolerance.The combination of capecitabine and irinotecan(XELIRI regimen)is an effective and well-tolerated regimen as the same as the FOLFIRI regimen for frist-line and second-line in treatment of advanced colorectal cancer." @default.
- W2387757924 created "2016-06-24" @default.
- W2387757924 creator A5087287319 @default.
- W2387757924 date "2010-01-01" @default.
- W2387757924 modified "2023-09-23" @default.
- W2387757924 title "Comparison of efficacy and toxicity between XELIRI and FOLFIRI regimens for advanced colorectal cancer" @default.
- W2387757924 hasPublicationYear "2010" @default.
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