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- W2387770081 abstract "The Pax gene family encodes a group of transcription factors and plays an essential role in organogenesis during embryonic development through regulating cell proliferation and self-renewal, migration of embryonic precursor cells, and the coordination of specific differentiation programs. This is supported by the fact that expression of Pax is dysregulated in several congenital disease. Alternative transcripts of Pax genes are identified in various tissues with specific location, and each isoforms has their own major molecular targets and signaling pathways. In this review, we provide a general background of the Pax genes, highlight the role of Pax proteins playing within specific tissues in terms of embryological development, and give a brief introduction of alternatively spliced isoforms of Pax protein identified." @default.
- W2387770081 created "2016-06-24" @default.
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- W2387770081 date "2008-01-01" @default.
- W2387770081 modified "2023-09-25" @default.
- W2387770081 title "Progress in the study of Pax gene family and its alternative splicing" @default.
- W2387770081 hasPublicationYear "2008" @default.
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