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- W2387830242 abstract "Objective To evaluate the protective effects of Salvia Miltiorrhiza injection on rabbits with endotoxic shock.Methods Rabbit model of endotoxic shock was produced in this study. Rabbits were randomly divided into the normal control group(group A,n=8), endotoxic shock group (group B,n=8) and Salvia Mfltiorrhiza injection treatment group (group C,n=8). At the time before and after the infusion of LPS 30min,60min,120min,180min,240min and 300min,blood samples were taken for measurement of the plasma alanine aminotransferase (ALT),creatinine(Cr),cardiac troponin I(cTnI),partial pressure of oxygen in artery ( PaO 2),tumor necrosis factor-α (TNF-α ) and interleukin-10 (IL-10).When the experiment was finished, autopsy was performaned,and the heart,lung,liver and kidney samples were taken for pathological study.Results After giving Salvia Miltiorrhiza injection, the plasma ALT, cTnI and TNF-α were significantly lower in group C than in group B.PaO 2 and IL-10 in group C were significantly higher than those in group B. Inflammation in liver,lung and heart tissue were alleviated in the groupc. Conclusion The results suggest that Salvia Miltiorrhiza injection has benefit effects on alleviating inflammation,and can prevent visceral organ damages in rabbits with endotoxic shock." @default.
- W2387830242 created "2016-06-24" @default.
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- W2387830242 date "2004-01-01" @default.
- W2387830242 modified "2023-09-23" @default.
- W2387830242 title "Protective effect of Salvia Miltiorrhiza injection on rabbits with endotoxic shock" @default.
- W2387830242 hasPublicationYear "2004" @default.
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