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- W2387885362 abstract "Objective: To investigate the pharmacokinetics property of Syringopicrosid in the tablets of colon-specific delivery coated and naked in vivo so that to provide the scientific data for the target effect. Methods: After orally administrated to rabbits, the blood samples were taken during the different times and the Syringopicrosid concentration in blood samples were determined with HPLC instrument. And then the pharmacokinetics parameters were taken by auto-fitting data with DAS2.0 pharmacokinetics software. Results: The Syringopicrosid in two preparations shows to be 2-compartment model after orally administrated to rabbits. The time appeared drug concentration in rabbit plasma to colon-specific delivery preparation was later than common tablet and the Tlag was about 4.6. Conclusion: The pharmacokinetics parameters showed that the colon-specific delivery tablet has good target effect in colon." @default.
- W2387885362 created "2016-06-24" @default.
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- W2387885362 date "2009-01-01" @default.
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- W2387885362 title "Study on Pharmacokinetics on Colon-specific Delivery Coated Tablet of Syringa Extract in Rabbit Body" @default.
- W2387885362 hasPublicationYear "2009" @default.
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