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- W2387898339 abstract "Objective:To compare the efficacy and safety of Ziprasidone and Risperidone in the treatment of female patients with schizophrenia.Methods:A total of 72 female patients were randomly assigned to Ziprasidone group(n=36) and Risperidone group(n=36),and received Ziprasidone(131.6±10.3) mg/d and Risperidone(5.9±1.3) mg/d treatment for 12 weeks respectively.The efficacy and adverse reaction were assessed with the Positive and Negative Syndrome Sale(PANSS),the Treatment Emergency Syndrome Scale(TESS) after the tveatment of 2,4,8,12 week.Results:The PANSS scores significantly decreased compared with the baseline sores in both groups since the second week(P0.05);the marked improvement rate was 50.0% and the total clinical effective rate was 77.8% in Ziprasidone group while 47.3% and 75.0% in Risperidone group,there were not significant differences between two groups(P0.05).There were similar rates of side effects between both groups(P0.05),Ziprasidone group was 47.2%(17/36) and Risperidone group was 52.8%(19/36)(P0.05).But the incidence of extrapyramidal symptoms,weight gain,high blood fat,hyperprolactin were significantly lower in the Ziprasidone group than those in the Risperidone group(P0.05).Conclusion:The results suggest Ziprasidone be of good efficacy and less adverse effects in the treatment of female patiens with schizophrenia." @default.
- W2387898339 created "2016-06-24" @default.
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- W2387898339 date "2011-01-01" @default.
- W2387898339 modified "2023-09-27" @default.
- W2387898339 title "A comparative study of Ziprasidone and Risperidone in the treatment of female patients with schizophrenia" @default.
- W2387898339 hasPublicationYear "2011" @default.
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