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- W2387908148 abstract "It is now established that CD4+CD25+regulatory T(Treg) cells expressing transcription factor FOXP3,a regulatory subpopulation of T cells,is indispensable for the maintenance of immunological self-tolerance and immune homeostasis.FOXP3 expression in Treg cells is specific and it is the key control factor for the development,activation and function of Treg cells.At present,CD4+FOXP3+T lymphocytes are often used to define Treg cells for scientific research.But recent studies show that human CD4+FOXP3+T cells are phenotypically and functionally heterogeneous,including suppressive and nonsuppressive T cells.The different functions of these cell subsets can be distinguished by phenotypic differences.This review discusses the recent research progress about phenotypic characteristics and functional heterogeneity of CD4+FOXP3+T cell subsets." @default.
- W2387908148 created "2016-06-24" @default.
- W2387908148 creator A5021997880 @default.
- W2387908148 date "2011-01-01" @default.
- W2387908148 modified "2023-09-23" @default.
- W2387908148 title "Research Progress in Heterogeneity of Human CD4~+FOXP3~+T Cells——Reveiw" @default.
- W2387908148 hasPublicationYear "2011" @default.
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