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- W2387950110 abstract "AIM:To investigate the mechanisms of Myospalax fontanieri bone extracts for macrophages activation. METHODS: Complete Freund's adjuvant was used to induce mouse celiac macrophage activation by ip,then peritoneal exudate cells were cultured in vitro in the present of LPS and IFN-γ,concentrations of IL-1β,IL-6,IL-12p40,and TNF-α were by ELISA measurement and the MAC-1 cell proportion was determined by FACS Calibur. RESULTS: Myospalax fontanieri bone had immunosuppressive effect on mouse celiac macrophages,and markedly decreased production of inflammatory Cytokine. CONCLUSION: Inhibition of inflammatory factor may be the mechanism of action for rheumatoid arthritis." @default.
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- W2387950110 date "2008-01-01" @default.
- W2387950110 modified "2023-09-25" @default.
- W2387950110 title "Effect of Myospalax fontanieri bone extracts on the function of CFA induced mice" @default.
- W2387950110 hasPublicationYear "2008" @default.
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