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- W2388016745 abstract "OBJECTIVE To determine the concentrations of lysophosphatidyl cholin in injectable HCPT liposome by HPLC method.METHODS A NH2 column(150mm×4.6mm,5μm) was used.The elution mobile phase was A:methanolchloroform(97∶3),B:2% oxalic acid-ethanol-(16∶84),A∶B=7∶3;Tthe flow rate was 0.8mL·min-1.and the detector was evaporative light-scattering detector(ELSD).RESULTS The linear range was 0.08～0.4mg·mL-1(r=0.9991) and the average recovery rate was 98.25%,with the RSD 1.6%.CONCLUSION The method is rapid,accurate and reliable,and can be used to determine the lysophosphatidyl cholin in liposome for injection." @default.
- W2388016745 created "2016-06-24" @default.
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- W2388016745 date "2009-01-01" @default.
- W2388016745 modified "2023-09-25" @default.
- W2388016745 title "A HPLC-ELSD method for assay of impurity in HCPT liposome for injection" @default.
- W2388016745 hasPublicationYear "2009" @default.
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