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- W2388021203 abstract "Objective To observe the correlation between endogenous hydrogen sulfide(H2S) and pulmonary arteries hypertension(PAH) in patients with chronic cor pulmonale at high altitude(HACCP).Methods The levels of plasma H2S,endothelin-1(ET-1),partial pressure of artery blood O2(PaO2) and partial pressure of in artery blood CO2(PaCO2) were measured in 72 patients with stable HACCP and 40 health subjects.Results Levels of plasma H2S and PaO2 were significantly lower in patients with HACCP than those in health subjects(all P0.01),and levels of plasma ET-1,mPAP and PaCO2 were significantly higher in patients with HACCP than those in health subjects(all P0.01).In patients with HACCP,the plasma H2S was negatively correlated with plasma ET-1,mPAP and PaCO2(r=-0.718,-0.692,-0.556,respectively,all P0.01),and was positively correlated with PaO2(r=0.583,P0.01).Conclision Endogenous H2S may be involved in the formation and development of PAH in HACCP and may be a noninvasive marker of PAH severity and prognosis of those patients." @default.
- W2388021203 created "2016-06-24" @default.
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- W2388021203 date "2012-01-01" @default.
- W2388021203 modified "2023-09-23" @default.
- W2388021203 title "The analysis of the correlation between endogenous hydrogen sulfide and pulmonary arteries hypertension in patients with chronic cor pulmonale at high altitude" @default.
- W2388021203 hasPublicationYear "2012" @default.
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