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- W2388097494 abstract "Objective:To investigate benefits and risks of aripiprazole and risperidone in the treatment of schizophrenia,to optimize clinical efficacy and safety,guide clinical treatment.Methods:60schizophrenia patients met the inclusion criteria were randomly divided into aripiprazole group and risperidone group,30cases of each group,each group were given aripiprazole and risperidone,8weeks for an effect,observed symptoms,made a positive and negative symptom scale symptom scale(PANSS)scores and adverse reactions scale(TESS)scores,to evaluate the clinical efficacy and safety.Results:The total effective rate of aripiprazole group and risperidone group was 93.33%,P0.05;the positive symptom scale(PANSS)score,negative syndrome scale(PANSS)score,scale total score of aripiprazole group and risperidone group were not statistically significant,all P0.05;headache,dry mouth,decreased blood pressure,insomnia of aripiprazole group was not statistically significant than and the risperidone group,all P0.05,but the extrapyramidal reactions,body mass increases,the incidence of amenorrhea galactorrhea of aripiprazole group was significantly lower than the risperidone group,all P0.05.Conclusion:The onset speed,security,compliance of aripiprazole were significantly better than risperidone,in particular,can significantly reduce the existing extrapyramidal reactions,weight gain,amenorrhea galactorrhea side effects,is preferred drug in the treatment of schizophrenia." @default.
- W2388097494 created "2016-06-24" @default.
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- W2388097494 date "2013-01-01" @default.
- W2388097494 modified "2023-09-28" @default.
- W2388097494 title "Analysis of Efficacy and Safety of Aripiprazole and Risperidone in the Treatment of Schizophrenia" @default.
- W2388097494 hasPublicationYear "2013" @default.
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