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- W2388164176 abstract "Objective:To discuss the clinical effects of two different schemes of methotrexate combined with mifepristone in the treatment of ectopic pregnancy. Method:80 patients with ectopic pregnancy were selected as the research objects,and all the patients were received in the obstetrics and gynecology of our hospital from February 2010 to February 2013,and they were randomly divided into group A with 0.4 mg/(kg·d)methotrexate combined with mifepristone and group B with 1 mg/kg methotrexate combined with mifepristone,then the clinical effects of the two groups were compared. Result:The total clinical effective rate of group B was 100%,and which was significantly higher than that of group A(97.%),and the difference between the two groups was not statistically significant(P0.05). There was no significant difference between the values of Blood beta hCG before treatment in the two groups(P0.05),and which decreased in the two groups after treatment 5 d and 10 d,but group B decreased significantly higher than group A(P0.05),after treatment 15 d and 30 d,there was no obvious difference(P0.05). The gastrointestinal response rate of group B was 17.5%,and the drop rate of white blood cells was 40%,and that of group A was 80% and 82.5% respectively,and the differences were statistically significant(P0.05). Conclusion:The therapy of methotrexate with 1 mg/kg combined with mifepristone in the treatment of ectopic pregnancy can guarantee the therapeutic effect,decrease the rate of adverse events,ensure the safety of drug use,meet the needs of patients with fertility,and has very positive clinical significance." @default.
- W2388164176 created "2016-06-24" @default.
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- W2388164176 date "2013-01-01" @default.
- W2388164176 modified "2023-09-23" @default.
- W2388164176 title "A Clinical Study of Two Application Schemes of Methotrexate Combined with Mifepristone in the Treatment of Ectopic Pregnancy" @default.
- W2388164176 hasPublicationYear "2013" @default.
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