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• W2388200435 abstract "Objective To systemically review the clinical curative effect and safety for the treatment of Parkinson's disease treated with traditional Chinese medicine( TCM). Methods To retrieve the randomized or half a randomized controlled trial documents of treating Parkinson's disease with TCM,which originate from the document of nearly 20 years. The quality evaluation of documents was measured using Jadad. The heterogeneity test,Meta- analysis of relevant data,funnel chart analysis and sensitivity analysis of documents were measured using Revman 4. 2. 2,which was provided by the Cochrane collaboration. Results There were 22 randomized controlled trials,including the treatment group( treated with TCM or TCM + levodopa preparations) of 877 cases and in control group( treated with levodopa preparations) of 827 cases,totaling 1704 patients. 2 studies,scored more than 3 points measured by Jadad,were high quality documents,and the rest were low quality documents. The results,measured by Meta- analysis, showed( 1) Total effective rate The merger of the two groups of UPDRS points rate RR( 95% CI) was 1. 25( 1. 13,1. 40),the difference was statistically significant,the sensitivity analysis in the statistical result is stable and reliable.( 2) UPDRS score changes Experimental UPDRS scores,Ⅱ,Ⅲ relative to the change of the baseline score significantly lower than control group,the combination of the two groups of WMD( 95% CI) were respectively-1.59(-2. 59,-0. 59),-1. 08(-1. 53,-0. 63),-1. 15(-1. 69,- 0. 61),the differences were statistically significant,funnel,asymmetry on figure points,note there published sex bias.( 3) Adverse reactions Experimental group and control group in the gastrointestinal tract reaction,constipation,insomnia,mental symptoms,switch phenomenon,the incidence of hypotension,agent at the end of the phenomenon more significant difference,salivate,dizziness was no statistical difference. Conclusion The existing clinical research evidence showed that using TCM can relieve the clinical symptoms of Parkinson's disease,improve the function of the patients,improve their ability of daily life activities and motor function,and high safety,compared with using western medicine alone. Combined TCM and western medicine to treat Parkinson's disease may be superior to western medicine alone,but because of the limitations of samples' quantity and quality,we still needs more high quality large sample randomized controlled trial to confirm." @default.
• W2388200435 created "2016-06-24" @default.
• W2388200435 creator A5021860320 @default.
• W2388200435 date "2014-01-01" @default.
• W2388200435 modified "2023-09-24" @default.
• W2388200435 title "Systemically review of the clinical curative effect of Parkinson's disease treated with traditional Chinese medicine(TCM)" @default.
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