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- W2388213426 abstract "Objective KAI1 gene is a specific metastasis suppressor gene, and its protein product is KAI1 /CD82. The relationship between KAI1 /CD82 expression and colon cancer patient prognosis was investigated. Methods 64 colon tumor specimens were detected and analyzed for their KAI1 /CD82 protein expression level with immunohistochemical method, the paraffin embedded tissue sections were incubated with anti KAI1 antibody. The Student's t test and the Kaplan Meier method were used. Results The KAI1 /CD82 protein was located in the membrane of colon tumor cells with a positive rate of 51.56%. The statistical evaluation showed that the expression of KAI1 /CD82 protein had a close relation with lymph node metastasis and distant metastasis as well as clinical stages, but was not related with age, gender, tumor size, differentiation and tumor location in vivo. Surviving time for the patients after being operated was dramatically higher with positive expression of KAI1 /CD82(54.27±21.51months) than those with negative one(37.55± 15.17 months). Conclusion KAI1 /CD82 expression is closely correlated with the colon tumor stages, lymph node metastasis and distant metastasis, which,together with other indexes, may be used as an index for prognosis of colon tumor, and will be significant for instructing further treatment." @default.
- W2388213426 created "2016-06-24" @default.
- W2388213426 creator A5058837031 @default.
- W2388213426 date "2002-01-01" @default.
- W2388213426 modified "2023-09-28" @default.
- W2388213426 title "The clinical significance of KAI1 /CD82 expression in colon tumor" @default.
- W2388213426 hasPublicationYear "2002" @default.
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