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- W2388259325 abstract "Objective To detect the clinical research and diagnosis meaning of TNF-α,IL-6,IL-8 and IL-10 's serum concentration of children mycoplasmal pneumonia.Method Used the method of double antibody sandwich ELISA to test TNF-α,IL-6,IL-8 and IL-10 's serum concentration of 78 children with mycoplasmal pneumonia( experimental group) and 78 healthy children( control group).We observed changes of immune factors and clinical manifestations of two groups of children.Result Serum concentration of TNF-α,IL-6,IL-8 and IL-10 of children with mycoplasmal pneumonia was more higher than that of healthy children,the difference was statistically significant( P 0.05).Cytokine concentration determines the severity of pneumonia in a certain range.After appropriate treatment,measured in children 's serum factor concentration was greatly reduced compared with those before treatment,but slightly higher than that of the healthy children,the difference was not significant( P 0.05).Pneumonia in children with the chest X-ray examination found factor concentration and no fibrosis pulmonary fibrosis children serum and pleural effusion pleural effusion,factor concentration increased significantly;the difference was statistically significant( P 0.05).Close to the factor concentrations in serum and pleural effusion in children without fibrosis of lung,and there was no obvious difference between the data( P 0.05).Conclusion Children mycoplasma pneumonia is mainly cause by mycoplasma pneumonia invades the human body immune system,which active and produce a large number of TNF- α release,IL-6,IL-8 and IL-10 and other immune factors,and the immune factors is associated with lung whether fibrosis lesions.So the immune serum for concentration is the main basis for the development of diagnosis of mycoplasmal pneumonia in children." @default.
- W2388259325 created "2016-06-24" @default.
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- W2388259325 date "2014-01-01" @default.
- W2388259325 modified "2023-09-26" @default.
- W2388259325 title "Clinical implications of TNF-α,IL-6,IL-8 and IL-10's serum concentration of children mycoplasmal pneumonia" @default.
- W2388259325 hasPublicationYear "2014" @default.
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