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- W2388404802 abstract "PurposeTo investigate the synergistic effect of the extract of Rhodiola rosea L.and CoQ_(10) on Alzheimer′s disease.MethodsInhibitory effect of cholinesterase in vitro was measured by ellman colorimetry,and the injured nerve cells by an in vitro model of neuronal impairment treating PC_(12) cells with NaCN and glucose (deprivation) was used.The dysmnesia model of acquired learning induced by scopolamine was also used.The ability of learning and memory was measured by water maze task.The activity of cholinesterase in cortex of model animal was determined.The activity of MAO,SOD and MDA was determined in blood serum.ResultsThe extract of Rhodiola rosea L.and CoQ_(10) were shown to inhibit cholinesterase in vitro and had effective action on protecting impaired nerve cells.The learning and memory of rats with AD was also improved.ConclusionThe extract of Rhodiola rosea L.and CoQ_(10) on Alzheimer′s disease have the synergistic effects." @default.
- W2388404802 created "2016-06-24" @default.
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- W2388404802 date "2006-01-01" @default.
- W2388404802 modified "2023-09-25" @default.
- W2388404802 title "Study on the synergistic effects of the extract of Rhodiola rosea L.and Co Q_(10) onimproving the ability of learning and memory in mice" @default.
- W2388404802 hasPublicationYear "2006" @default.
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