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- W2388406009 abstract "Objective To investigate the effect and the mechanism of kidney-reinforcing Chinese herb(Zishenwan) on biomechanics of lumbar vertebrae in ovarietomized osteoporosis rats. Methods Female SD rats(n=66,15 weeks old) were randomly assigned to 6 groups(11 each) and the control group were sham operated;the others 5 groups underwent ovariectomy Medicines were initiated 2 weeks after surgery lasting 12 wekks,and then the rats were sacrificed.The lumbars were taken out,and their biomechanics capabilities were determined.The serum level of E_2 and ALP were measured. Results The lumbar biomechanics properties worsened significantly, with elevated ALP level and decreased E_2 level in the study group.Those rats trcated with Zishenwan showed different effect against the changes (P0.05). Conclusions Zishenwan can improve the biomechanics of bones in ovariectomized osteoporosis rats,and this effect is associated with the elevated E_2 level and reduced ALP level which may further suppress the bone turnover and improve the bone formation." @default.
- W2388406009 created "2016-06-24" @default.
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- W2388406009 date "2006-01-01" @default.
- W2388406009 modified "2023-09-23" @default.
- W2388406009 title "Effect and mechanism of Zishenwan on biomechanics of bone in ovariectomized osteoporosis rats" @default.
- W2388406009 hasPublicationYear "2006" @default.
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