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- W2388501301 abstract "AIM To explore the effect and safety of budesonide inhalation by nose on combined allergic rhinitis and asthma syndrome(CARAS).METHODS Eighty-two patients with CARAS were randomly divided into two groups.All patients were treated by atomization pots.The patients in the nose group(n = 40) received budesonide aerosol by nose-suction nozzle,while the others in the mouth group(n = 42) received budesonide aerosol by mouth - suction nozzle.The doses of the two groups were the same and the courses were both 8 weeks. The symptoms scorings,lung function(FEV_1,PEF),levels of serum total IgE and eosinophil absolute values were observed before and after the treatment.RESULTS The symptoms scorings of nasal and thorax,the levels of IgE,and the eosinophil absolute values in both groups decreased obviously after the treatment(P 0.01). The symptoms scorings and the level of IgE in the nose group were obviously lower than those in the mouth group (P 0.05 or P 0.01),while no significant difference in the eosinophil absolute values between two groups(P 0.05).The levels of FEV_1 and PEF increased significantly in both groups,and those in the nose group were higher(P 0.01).There was no severe adverse reaction in the two groups.CONCLUSION Budesonide inhalation by nose in treating CARAS can obviously improve symptoms and lung functions,reduce serum total IgE level,with few adverse reaction.Budesonide inhalation by nose is superior to inhalation by mouth." @default.
- W2388501301 created "2016-06-24" @default.
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- W2388501301 date "2012-01-01" @default.
- W2388501301 modified "2023-09-24" @default.
- W2388501301 title "Budesonide inhalation by nose in treating 40 patients with combined allergic rhinitis and asthma syndrome" @default.
- W2388501301 hasPublicationYear "2012" @default.
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