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- W2388565560 abstract "Objective To investigate the expression of claudin-4 mRNA in gastric cancer,and to explore the relationship of biologic action in gastric cancer.Methods The reverse transcriptase PCR was carried out to detect the level of claudin-4 mRNA from 31 gastric adenocarcinoma and 10 normal samples.Results The relative level of claudin-4 mRNA in the normal gastric mucosa is lower than that in the primary gastric cancer(P0.05).The relative level of claudin-4 mRNA in well-differentiated gastric adenocarcinoma is lower than that in poorly differentiated.The relative level of claudin-4 mRNA in lymph node metastasis cancer is higher than that in no lymph node metastasis cancer(P0.05).The relative level of claudin-4 mRNA in the tissue of gastric carcinoma of infiltration of mucosa and bellow mucosa are lower than that in the tissue of gastric carcinoma of infiltration of muscle and serous membrane(P0.05).Coclusions Up-regulated expression of claudin-4 mRNA play an important role in gastric tumor.It may have the active role in invasion and metastasis of gastric tumor." @default.
- W2388565560 created "2016-06-24" @default.
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- W2388565560 date "2008-01-01" @default.
- W2388565560 modified "2023-09-23" @default.
- W2388565560 title "Expression and significance of claudin-4 mRNA in human gastric carcinoma" @default.
- W2388565560 hasPublicationYear "2008" @default.
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