Matches in SemOpenAlex for { <https://semopenalex.org/work/W2388568739> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2388568739 abstract "AIM: To study the changes of neurokinin A (NKA) and NKA mRNA in lung tissues of asthmatic guinea pigs exposed to chronic cigarette smoke and investigate the mechanism. METHODS: The model of asthma in guinea pigs was made by exposure to aerosolized ovalbumin and animals were randomly assigned into: ① inhale cigarette smoke (ICS) 2 weeks before provoked; ② ICS 2 weeks after provoked; ③ 2 weeks after provoked (no-ICS); ④ asthma (no-ICS before provoked); ⑤ normal control. The contents of NKA in lung tissues were detected by ELISA and NKA mRNA expression was detected by reverse transcription-polymerase chain reaction. RESULTS: ① The levels of NKA and NKA mRNA expression in lung tissues of asthma group were significantly higher than those in normal control group (P0.01, respectively); ② The levels of NKA and NKA mRNA expression in lung tissues of ICS 2 weeks before provoked were significantly higher than those in asthma group (P0.01, respectively); ③ The levels of NKA and NKA mRNA expression in lung tissues of ICS 2 weeks after provoked were significantly higher than those in no-ICS after provoked (P0.01, respectively).CONCLUSIONS: ① NKA probably takes part in the pathogenesis of asthma in guinea pigs induced by ovalbumin. ② Chronic cigarette smoke may increase the levels of NKA in lung tissue of asthmatic guinea pigs. ③ Chronic cigarette smoke may up-regulate the NKA mRNA expression in lung of asthma and then elevate NKA contents." @default.
- W2388568739 created "2016-06-24" @default.
- W2388568739 creator A5043496571 @default.
- W2388568739 date "2005-01-01" @default.
- W2388568739 modified "2023-09-23" @default.
- W2388568739 title "Neurokinin A and gene expression in lung of asthmatic guinea pigs exposed to chronic cigarette smoke" @default.
- W2388568739 hasPublicationYear "2005" @default.
- W2388568739 type Work @default.
- W2388568739 sameAs 2388568739 @default.
- W2388568739 citedByCount "0" @default.
- W2388568739 crossrefType "journal-article" @default.
- W2388568739 hasAuthorship W2388568739A5043496571 @default.
- W2388568739 hasConcept C104317684 @default.
- W2388568739 hasConcept C105580179 @default.
- W2388568739 hasConcept C118303440 @default.
- W2388568739 hasConcept C126322002 @default.
- W2388568739 hasConcept C134018914 @default.
- W2388568739 hasConcept C170493617 @default.
- W2388568739 hasConcept C203014093 @default.
- W2388568739 hasConcept C2776042228 @default.
- W2388568739 hasConcept C2776533618 @default.
- W2388568739 hasConcept C2776946954 @default.
- W2388568739 hasConcept C2777056410 @default.
- W2388568739 hasConcept C2777714996 @default.
- W2388568739 hasConcept C2778815084 @default.
- W2388568739 hasConcept C2780942790 @default.
- W2388568739 hasConcept C55493867 @default.
- W2388568739 hasConcept C71924100 @default.
- W2388568739 hasConcept C86803240 @default.
- W2388568739 hasConcept C8891405 @default.
- W2388568739 hasConceptScore W2388568739C104317684 @default.
- W2388568739 hasConceptScore W2388568739C105580179 @default.
- W2388568739 hasConceptScore W2388568739C118303440 @default.
- W2388568739 hasConceptScore W2388568739C126322002 @default.
- W2388568739 hasConceptScore W2388568739C134018914 @default.
- W2388568739 hasConceptScore W2388568739C170493617 @default.
- W2388568739 hasConceptScore W2388568739C203014093 @default.
- W2388568739 hasConceptScore W2388568739C2776042228 @default.
- W2388568739 hasConceptScore W2388568739C2776533618 @default.
- W2388568739 hasConceptScore W2388568739C2776946954 @default.
- W2388568739 hasConceptScore W2388568739C2777056410 @default.
- W2388568739 hasConceptScore W2388568739C2777714996 @default.
- W2388568739 hasConceptScore W2388568739C2778815084 @default.
- W2388568739 hasConceptScore W2388568739C2780942790 @default.
- W2388568739 hasConceptScore W2388568739C55493867 @default.
- W2388568739 hasConceptScore W2388568739C71924100 @default.
- W2388568739 hasConceptScore W2388568739C86803240 @default.
- W2388568739 hasConceptScore W2388568739C8891405 @default.
- W2388568739 hasOpenAccess W2388568739 @default.
- W2388568739 hasRelatedWork W2343908399 @default.
- W2388568739 hasRelatedWork W2351164794 @default.
- W2388568739 hasRelatedWork W2367036501 @default.
- W2388568739 hasRelatedWork W2370776555 @default.
- W2388568739 hasRelatedWork W2372433485 @default.
- W2388568739 hasRelatedWork W2374875353 @default.
- W2388568739 hasRelatedWork W2375238083 @default.
- W2388568739 hasRelatedWork W2379824406 @default.
- W2388568739 hasRelatedWork W2380415044 @default.
- W2388568739 hasRelatedWork W2381482954 @default.
- W2388568739 hasRelatedWork W2384745228 @default.
- W2388568739 hasRelatedWork W2391276870 @default.
- W2388568739 hasRelatedWork W2395842662 @default.
- W2388568739 hasRelatedWork W2410084970 @default.
- W2388568739 hasRelatedWork W3029149789 @default.
- W2388568739 hasRelatedWork W3031234675 @default.
- W2388568739 hasRelatedWork W3032013009 @default.
- W2388568739 hasRelatedWork W3049203210 @default.
- W2388568739 hasRelatedWork W3152012036 @default.
- W2388568739 hasRelatedWork W3194639418 @default.
- W2388568739 isParatext "false" @default.
- W2388568739 isRetracted "false" @default.
- W2388568739 magId "2388568739" @default.
- W2388568739 workType "article" @default.