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- W2388578085 abstract "Objective To study the expression of vascular endothelial growth factor(VEGF),gelatinase A in pterygium and investigate the interrelationships between VEGF and gelatinase A in the development of pterygium.Methods Thirty-one pterygium were obtained from pterygia patients and made by cryosection.The immunohistochemical method was used to test the expression of VEGF and gelatinase A in human pterygium and conjunctiva.Results The positive rate of VEGF and gelatinase A expression in pterygia epithelium was higher than that in normal conjunctival tissue (χ~2=29.187,P0.001),and gelatinase A expression in pterygia epithelium was also higher than that in normal conjunctival tissue(χ~2=39.00,P0.001).The number of weak positive and strong positive of VEGF in aggressive and quiescent pterygium were 4 、19 and 4、4 respectively(χ~2=4.216,P0.05);The number of weak positive and strong positive of gelatinase A in aggressive and quiescent pterygium were 2 、21 and 6、2 respectively(χ~2=12.816,P0.001).Conclusion Both VEGF and gelatinase A express too much in pterygium,there is a positive correlation between the VEGF and gelatinase A expression and pathological stage of pterygium.They may play an important role in the occurrence and invasion of pterygium." @default.
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- W2388578085 date "2006-01-01" @default.
- W2388578085 modified "2023-09-22" @default.
- W2388578085 title "Expression of gelatinase A and vascular endothelial growth factor in pterygia" @default.
- W2388578085 hasPublicationYear "2006" @default.
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