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- W2388602181 abstract "Aim: To study the role of serum interleukin-6(IL-6)and tumor necrosis factor alpha(TNF-α) in hypertensive disorder complicating pregnancy patients. Methods: Serum IL-6 and TNF-α levels were measured by using radioimmunoassay in 26 severe pre-eclampsia patients, 27 mild pre-eclampsia patients,and 30 normal pregnant women. Results:The levels of serum IL-6 and TNF-α were (220.08±31.82) ng·L -1 and (1.79±0.25) μg·L -1 in group of pre-eclampsia,which were higher than those ((114.63±14.63) ng·L -1 and (1.16±0.13) μg·L -1 ) in group of normal pregnants (P0.05). The levels of IL-6 and TNF-α were (246.27±22.76) ng·L -1 and (1.99±0.17) μg·L -1 in group of severe pre-eclampsia,(199.13±20.79) ng·L -1 and (1.60±0.14) μg·L -1 in group of mild pre-eclampsia,which were significantly higher than those in the group of normal pregnants,and lower than those in group of severe pre-eclampsia(P0.05).The expression of serum IL-6 and TNF-α in patients with pre-eclampsia had a close relationship with the state of the illness. Conclusion: The higher level of IL-6 and TNF-α plays an important role in the pathogenesis and development of hypertensive disorder complicating pregnancy." @default.
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- W2388602181 date "2005-01-01" @default.
- W2388602181 modified "2023-09-27" @default.
- W2388602181 title "Detection of serum interleukin-6 and TNF-α in hypertensive disorder complicating pregnancy patients" @default.
- W2388602181 hasPublicationYear "2005" @default.
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