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- W2388647597 abstract "Objective To investigate the effect of emodin in preventing and treating hypertrophic scar. Methods The hypertrophic scar samples were collected from 6 patients admitted to our hospital. The fibroblasts of hypertrophic scar were cultured and treated with emodin (respectively 20, 40, 60 μg/ml) in culture medium. The proliferation of fibroblasts was detected by MTT colorimestric assay and the fluorescence intensity of intracellular free calcium was investgated by confocal laser microscopy. Results The proliferation of fibroblasts was inhibited significantly after emodin treatment in a dose-dependent manner, while the fluorescence intensity of intracellular free calcuim was significantly increased. Conlusion Emodin can inhibit the proliferation of hypertrophic scar fibroblasts, which mechanism may be related to increasing intracellular calcium." @default.
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- W2388647597 date "2007-01-01" @default.
- W2388647597 modified "2023-09-23" @default.
- W2388647597 title "Effect of emodin on proliferation and intracellular free calcium of hypertrophic scar fibroblasts in vitro" @default.
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