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- W2388647819 abstract "Objective To study the expressions of human telomerase reverse transcriptase(hTERT) in human gastric adenocarcinoma tissue and benign lesions,and to investigate the relationship between hTERT and the progression of gastric adenocarcinoma.Methods The expressions of hTERT in gastric adenocarcinoma tissue and the gastric benign tissues from 75 patients and 11 normal people were measured by immunohistochemistry(SP method).Image Pro Plus(IPP) was used as the method of quantitative image analysis on immunohistochemical slide image.Results There were no significant differences among the expressions of hTERT in the normal gastric tissue(119.44±54.12),chronic gastritis(159.94±78.67) and gastric ulcer(266.55±81.84)(P0.05).But the differences were significant compared with the gastric adenocarcinoma(early: 3 129.88±634.34,and advanced: 5 288.45±1 303.64)(P0.01).There were close relationships among the expression level of hTERT with the differentiation degree,depth of invasion,lymph node metastasis,distant metastasis,pathological sort and TNM of the tumor(P0.05).Conclusion Over-expressed hTERT is in great correlation with the progress of gastric adenocarcinoma and an important factor of poor prognosis." @default.
- W2388647819 created "2016-06-24" @default.
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- W2388647819 date "2009-01-01" @default.
- W2388647819 modified "2023-09-23" @default.
- W2388647819 title "Relationship between human telomerase reverse transcriptase(hTERT) and clinical pathological features in gastric adenocaicinoma" @default.
- W2388647819 hasPublicationYear "2009" @default.
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