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- W2388649578 abstract "Objective To observe the changes in glycosylated serum protein (GSP) level in patients with diabetes complicating acute coronary syndrome (ACS),and explore the clinical significance of GSP in diagnosing diabetes complicating ACS. Methods Seventy-two patients with type 2 diabetes (T2DM) complicating coronary heart disease (CHD),admitted from 2008-01-01 to 2008-12-31,were enrolled in the present study. According to the types of CHD,stable angina (SA) and ACS,27 T2DM patients complicated with SA were assigned to the control group and 45 with ACS to the study group. The levels of fasting plasma glucose (FPG),GSP,hemoglobin A1c (HbA1c),total cholesterol (TC),total triglyceride (TG),high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were measured. The 72 patients were subsequently divided into the exposure group (GSP210μmol/L,n=40) and non-exposure group (GSP≤210μmol/L,n=32) according to their GSP levels. An OR χ2 test was applied to analyze the difference in the risk of complicating ACS between the two groups. Results The levels of TC,TG,LDL-C and HbA1c were slightly higher in study group but no statistically significant difference was observed (P0.05). In comparison with the control group,the levels of FPG and GSP were significantly higher (P0.05),while HDL-C was lower (P0.05) in study group. Both GSP level and ACS incidence in exposure group (275.055±57.88μmol/L,75.0%) were higher than that in non-exposure group (173.281±24.28,46.9%,P0.05). The risk of complicating ACS in exposure group was 3.400 fold of that in non-exposure group (χ2=6.000,OR=3.400,P=0.014,95% CI:1.254-9.216). Conclusions Compared with HbA1c,the elevation of GSP level is more significant in the diagnosis of T2DM patients with ACS. Detection of GSP may be helpful for early diagnosis and risk appraisal." @default.
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- W2388649578 date "2009-01-01" @default.
- W2388649578 modified "2023-09-23" @default.
- W2388649578 title "The clinical significance of glycosylated serum protein in patients with diabetes complicating acute coronary syndrome" @default.
- W2388649578 hasPublicationYear "2009" @default.
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