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- W2388654339 abstract "Objective To observe the effect of Shengmai Injection on soluble intercellular adhesion molecule-1(sICAM-1) and soluble P-selectin(sP-sel) in the patients with isolated systolic hypertension and to study the mechanism of Shengmai Injection to treat essential hypertension.Methods 45 patients with isolated systolic hypertension were treated with Shengmai Injection plus amlodipine besylate,and 45 patients with isolated systolic hypertension were remedied with amlodipine besylate only as control.The levels of sICAM-1 and sP-sel in the blood were tested before treatment and after 8 weeks treatment course.Results After 8 weeks treatment,the systolic pressure in both the two groups was lower than 140 mm Hg.Moreover,the levels of sICAM-1 and sP-sel in serum were decreased after treatment,but which in the group of Shengmai injection plus amlodipine besylate decreased more obviously compared with the only amlodipine besylate group.Conclusion Shengmai Injection has the significant treatment effect on the patient with isolated systolic hypertension.Shengmai Injection might have the protective and repairing effect on vascular endothelial cells in hypertension via regulating the expression of adhesion molecules and inhibiting inflammatory reaction." @default.
- W2388654339 created "2016-06-24" @default.
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- W2388654339 date "2010-01-01" @default.
- W2388654339 modified "2023-09-28" @default.
- W2388654339 title "Effect of Shengmai Injection on soluble adhesion molecules in patient with isolated systolic hypertension" @default.
- W2388654339 hasPublicationYear "2010" @default.
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