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- W2388688450 abstract "Objective To observe the curative effects of Shuangligan and glycine,drugs used to contain intestinal endotoxemia(IETM),in rats with severe acute pancreatitis(SAP).Methods Eighty female or male Wistar rats(260±20)g in weight were provided by Experimental Animal Center of Shanxi Medical University.These rats were randomized into the sham operation(SO) group,SAP model group,Shuangligan group and Glycine group,20 in each.Changes of plasma endotoxin(ET),serum amylase(AMY),pathological scores of pancreas and case fatality in each group were observed over a 48-hour period.Results The rats in SO group experienced long-term survival and lowest levels in plasma ET,serum AMY and pathological score versus the highest levels in these indicators shown by SAP group.Both Shuangligan and Glycine treatment groups showed statistical improvement in plasma ET,serum AMY and pathological score compared with SAP group.Conclusion Both Shuangligan and Glycine may ameliorate the pathological damage in pancreas,leading to lowered level of case fatality for SAP rats." @default.
- W2388688450 created "2016-06-24" @default.
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- W2388688450 date "2007-01-01" @default.
- W2388688450 modified "2023-09-28" @default.
- W2388688450 title "An observational study on curative effects of Shuangligan and glycine in rats with severe acute pancreatitis" @default.
- W2388688450 hasPublicationYear "2007" @default.
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