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- W2388715287 abstract "ObjectiveCompare the difference of the interleukin-6(IL-6) gene promoter methylation between patients with chronic periodontitis and healthy people to find out the relation between IL-6 gene promoter methylation and susceptibility of periodontitis.MethodsCP group,44 patients with periodontitis;H group,45 cases of periodontal healthy persons.DNA was taken by swabbing buccal mucosa exfoliated cells with cotton and was detected by methylation-specific polymerase chain reaction method.ResultsIL-6 promoter methylation was positive in 30 patients of CP group,and the positive rate was 68.18%;H group,IL-6 promoter methylation was positive in 42 persons of H group,and the positive rate was 93.33%.The difference between the two groups had statistical significance(χ~2=9.108,P=0.003).ConclusionIL-6 gene promoter methylation status may be associated with susceptibility of chronic periodontitis." @default.
- W2388715287 created "2016-06-24" @default.
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- W2388715287 date "2013-01-01" @default.
- W2388715287 modified "2023-09-26" @default.
- W2388715287 title "Interleukin-6 gene promoter methylation in patients with chronic periodontitis" @default.
- W2388715287 hasPublicationYear "2013" @default.
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