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- W2388766589 abstract "Objective To explore whether the chorionicity can be diagnosed during middle and late trimesters by measuring the thickness of the inter-twin membrane with three-dimensional(3D) ultrasound,and to evaluate the accuracy and the reproducibility of this technique.Methods Totally 113 twin pregnancies's chorionicities were assessed between 17 and 36 weeks of gestation prenatally and confirmed postnatally.The dividing membranes between the fetuses were visualized and measured with 2D and 3D ultrasound,respectively.The receiver operator characteristic(ROC) curve was drawn to determine the optimal cut-off point of the thickness of the membranes for predicting chorionicity.Intraclass correlation coefficients and Kappa index were calculated to evaluate the inter-and intraoperator variability.The accuracy of prenatal assessment of chorionicity by 2D and 3D ultrasound measurement of membrane thickness was also compared.Results ①The best cut-off of membrane thickness for discriminating monochorionic from dichorionic twinning was 1.8 mm.②When measuring the thickness of the membranes in twins using 3D ultrasound,there was a high degree accuracy in the determination of chorionicity.The area under the ROC curve,sensitivity and specificity was 0.906,95.35% and 94.29%,respectively.③With 3D ultrasound,the intraclass correlation coefficients for variability intra-and interoperator was 0.98 and 0.98,respectively.Kappa indices for variability interoperator was 0.96.Conclusion It is feasible,accurate and reproducible to assess chorionicity by measuring the intra-amniotic membrane thickness with 3D ultrasound in twin pregnancies during the second and third trimesters.The intra-amniotic membrane thickness is an effective supplementary indicator." @default.
- W2388766589 created "2016-06-24" @default.
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- W2388766589 date "2011-01-01" @default.
- W2388766589 modified "2023-09-23" @default.
- W2388766589 title "Determining chorionicity in twin pregnancies during the second and third trimesters: Three-dimensional ultrasonic measurement of inter-twin membrane thickness" @default.
- W2388766589 hasPublicationYear "2011" @default.
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