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- W2388842042 abstract "4-(4-Hydroxyphenethyl)benzene-1,2-diol is a new inhibitor against Helicobacter Pylori urease.The inhibition mechanism was herein investigated through enzyme kinetics methods,and the results revealed that 4-(4-hydroxyphenethyl)benzene-1,2-diol was competitive inhibitor of urease with a Ki value of 1.48 μmol/L.The chemical stabilitiy and the competitive mechanism of 4-(4-hydroxyphenethyl)-benzene-1,2-diol strongly suggested that it could be used as a lead compound for rational drug design to find active compound and as a potential urease inhibitor for treatment of gastritis and peptic ulcer." @default.
- W2388842042 created "2016-06-24" @default.
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- W2388842042 date "2012-01-01" @default.
- W2388842042 modified "2023-09-22" @default.
- W2388842042 title "Study on the Inhibition Mechanism of 4-(4-Hydroxyphenethyl) Benzene-1,2-Diol on Urease" @default.
- W2388842042 hasPublicationYear "2012" @default.
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