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- W2388842266 abstract "Objectives To investigate the clinical characteristics and therapy of type 2 diabetes mellitus(T2DM) in children.Methods The clinical records of 52 hospitalized children with T2DM from Jan.2003 to Mar.2012 were retrospectively analyzed.Results Eight(15.38%) of 52 patients(23 male and 29 female) were overweight,33 patients(63.46%) were obese,and 33 patients(63.46%) had family history of diabetes and most of patients presented with typical symptoms.Six cases(11.54%) were complicated by diabetic ketoacidosis,43 cases(82.69%) presented with dyslipidemia,and 22 cases(42.31%) had hypertension,13 cases(25.00%) were with non-alcoholic fatty liver,and 3 female cases with polycystic ovary syndrome.The insulin resistance index(HOMA-IR) and insulin secretory function(HOMA-IS) were calculated in 24 patients.The HOMA-IR was elevated with blood glucose increased,but the difference was not statistically significant.For treatment,2 cases(3.85%) were treated with dietary,exercise and behavior intervention,10 cases(19.23%) with oral metformin,and 15 cases(28.85%) with insulin administered subcutaneously,25 cases(48.08%) with insulin combined with metformin.Eighteen patients were followed up.Conclusions T2DM usually occurs in the older and obese children.Its incidence is increasing each year.The patients has various clinical manifestations,and with β cell disfunction and insulin resistance.The compliance of patients were poor." @default.
- W2388842266 created "2016-06-24" @default.
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- W2388842266 date "2013-01-01" @default.
- W2388842266 modified "2023-09-26" @default.
- W2388842266 title "Clinical analysis of 52 children with type 2 diabetes mellitus" @default.
- W2388842266 hasPublicationYear "2013" @default.
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