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- W2388866355 abstract "Objective To study the clinical features of metformin associated lactic acidosis in diabetes patients and their response to NaHCO3 treatment.Methods Clinical features,treatment and outcome of five diabetes patients with metformin associated lactic acidosis admitted to our department in 2010 were retrospectively analyzed.Results The diabetes courses of the five cases were five years to 20 years and all of them had been taking metformin with primary manifestations of digestive symptoms like retching,vomiting and abdominal distension.The severe cases had hypotension and multi-organ injuries.Laboratory test showed that pH decreased significantly,lactate level and anion gap(AG) increased significantly.All the patients recovered and discharged after limited supply of NaHCO3 and fluid,tissue maintaining perfusion and anti-infection treatment.Conclusion Diabetes patients with metformin associated lactic acidosis should be treated comprehensively and limited supply of NaHCO3 can achieve satisfactory efficacy." @default.
- W2388866355 created "2016-06-24" @default.
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- W2388866355 date "2012-01-01" @default.
- W2388866355 modified "2023-09-24" @default.
- W2388866355 title "Limited Supply of NaHCO3 for Diabetes Patients with Metformin Associated Lactic Acidosis" @default.
- W2388866355 hasPublicationYear "2012" @default.
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