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- W2388893557 abstract "Objective To determine the expression of E2F- 1 and MDM2 in the endometrial carcinoma and thesignificance. Methods The expressions of E2F-1 and MDM2 in endometrial cancer patients and normal endometrial tissueswere detected by immunohistochemistry S-P and the results were analysed. Results The expressions of E2F-1 and MDM2were located in the cytoplasm. The positive expression rates of E2F-1 and MDM2 in cancer patients were 73.33%(66/90) and56.67%(51/90)significantly higher than that in normal endometrial tissue(P 0.05). The expressions in endometrial cancershowed the statistically significant difference(P 0.05).In endometrial carcinoma, the expressions of E2F-1 and MDM2 werecorrelated with each other(P 0.05). Conclusion E2F-1 and MDM2 were highly expressed in the endometrial carcinoma,itcan reflect the malignant degree of carcinoma of endometrium The detection method is simple and easy to use and of guidingsignificance in prognosis of carcinoma of endometrium." @default.
- W2388893557 created "2016-06-24" @default.
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- W2388893557 date "2014-01-01" @default.
- W2388893557 modified "2023-09-25" @default.
- W2388893557 title "Expression and significance of E2F-1 and MDM2 in endometrial carcinoma patients" @default.
- W2388893557 hasPublicationYear "2014" @default.
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