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- W2388943078 abstract "Objective To demonstrate the effect of pantoprazole preventing stress ulcer in the mechanical ventilation patients. Methods 60 mechanical ventilated patients with respiratory failure due to severe pulmonary infection or chronic obstructive pulmanary disease were randomly divided into two groups. Besides same basic therapy,the observation group ( n = 30) were treated with pantoprazole ( 40 mg qd ivgtt) ,while the control group ( n = 30) were not treated with gastric acid inhibitor. Upper gastrointestinal bleeding occurred during treatment was surveyed,and if occurred,emergency gastroscopy was performed. The stress ulcer was diagnosed by gastroscopy. The hospital days were also recorded. Results The incidence of stress ulcer was significantly lower in the observation group than that in the control group ( 3. 3%,1/30 vs 20. 0%,6/30,P =0. 044) . The hospital days was also significantly less in the observation group than that in the control group ( 17. 5 d ± 4. 7 d vs 21. 3 d ± 6. 0 d,P = 0. 008) . Conclusion Pantoprazole could prevent stress ulcer in the mechanical ventilation patients with respiratory failure effectively,and shorten the hospital days." @default.
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- W2388943078 date "2013-01-01" @default.
- W2388943078 modified "2023-09-25" @default.
- W2388943078 title "Effect of pantoprazole preventing stress ulcer in the mechanical ventilation patients" @default.
- W2388943078 hasPublicationYear "2013" @default.
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