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- W2388943676 abstract "Objective:To study the influence of pretreatment with ketamine on the epidural analgesic effect of ropivacaine. Methods:60 ASAⅠ-Ⅱpatients scheduled for elective hypogastric surgeries were randomly divided into 2 equal groups,the control group(A) and ketamine group(B). After the surgeries,patients of both groups were subjected to PCEA (patient controlled epidural analgesia). In this procedure,patients of group(A) were given each 5 mL of 0.2% ropivacaine with addition of 0.0002% fentanyl analgesic mixture administered through an epidural catheter. Another 3 mL of the drug were injected 15 min later if no apparent analgesic effect was induced. Thereafter,a maintenance dose of 2 mL·h -1 was sustained for 24～48 h. 1 h before PCEA,patients of group (B) were given each 0.3 mg·kg -1 of ketamine administered through the epidural catheter. All other measures were the same as those taken for patients of group(A). Visual analogue scale(VAS) score and Bruggerman comfort scale (BCS) score were registered 4,8,16 and 24 h after the operation to assess the analgesic effect and the level of comfortableness,respectively. Results:The VAS scores in group (B) were significantly lower than those in group (A),while the BCS scores in group(A) were significantly lower than those in group(B) ( P 0.05 in both cases). Conclusion:Pretreatment with ketamine was shown to enhance the analgesic effect of ropivacaine." @default.
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- W2388943676 date "2004-01-01" @default.
- W2388943676 modified "2023-09-25" @default.
- W2388943676 title "Influence of Pretreatment with Ketamine on the Epidural Anesthesic Effect of Ropivacaine" @default.
- W2388943676 hasPublicationYear "2004" @default.
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