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- W2388950425 abstract "Objective:To investigate the association of eNOS gene G894T polymorphism and the development and progression of gastric cancer.Methods:PCR-RFLP method was used to determine the genotypes of eNOS G894T gene polymorphism in 324 gastric cancer patients and 200 cancer-free controls in Han Population of Fujian Province.Results:(1)In the case and control group,G/G genotype frequencies were 76.5%(248/324) and 73.0%(146/200)respectively;G/T+T/T genotype frequencies were 23.5%(76/324) and 27.0%(54/200)respectively;G allele frequencies were 88.0%(570/648)and 86.3%(345/400) respectively;T allele frequencies were 12.0%(78/648)and 13.7%(55/400)respectively.The comparisons between the case group and control group showed no significant difference in genotype and allele frequencies(all P0.05);When case group was subdivided as diffuse-type and intestinal-type,the comparisons between the two subgroups and control group respectively also showed that not any genotype or allele increased the risk of gastric cancer(all P0.05).(2)No statistically significant correlations existed between eNOS G894T polymorphism and several clinicopathological features of gastric cancer(all P0.05).Conclusion:No association is found between eNOS gene G894T polymorphism and the development and progression of gastric cancer in Han Population of Fujian Province." @default.
- W2388950425 created "2016-06-24" @default.
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- W2388950425 date "2010-01-01" @default.
- W2388950425 modified "2023-09-28" @default.
- W2388950425 title "Association of the eNOS G894T polymorphism with the development and progression of gastric cancer" @default.
- W2388950425 hasPublicationYear "2010" @default.
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