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- W2388957557 abstract "OBJECTIVE To prepare naproxen calcium alginate gel micro pills,and determine the release of the drug.METHODS The formulation was optimized by uniform design.The concentration of naproxen in the release medium was assayed by UV-VIS spectrophotometry.The dissolution behavior of the pills was determined in vitro.RESULTS The gel beads micro pills prepared under the optimum condition were with a good appearance,and the drug loading was(62.2±1.8)%.The drug released from the gel micro pills was less than 3.1% in SGF during 2 hours,and more than 95% in SIF during 45 minutes.CONCLUSION The gel micro pills have a good appearance with high drug loading and the enteric release property." @default.
- W2388957557 created "2016-06-24" @default.
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- W2388957557 date "2007-01-01" @default.
- W2388957557 modified "2023-09-23" @default.
- W2388957557 title "Preparation and in vitro release characterization of naproxen calcium alginate gel micro pills" @default.
- W2388957557 hasPublicationYear "2007" @default.
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