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- W2388960147 abstract "OBJECTIVE To observe the effect of seaweed polysaccharide on bleomycin(BLM) induced interstitial pulmonaryfbrosis(IPF) in rats.METHODS Inject BLM into tracheae of rats to establish the IPF model:adminstrate seaweed polysaccharide(at dose 50,100mg·mL-1,i.g.)to the models.On the 0th,7th,14th and 28th day of model-establishing,measure the level of hydroxyproline at lungs.RESULTS On the 7th and 28th day of model-establishing,the hydroxyproline concentration of the two groups rats(at the two doses of seaweed polysaccharide) aresignificantly lowered,comparing to model control group(P0.05):on the 14th day,the high dose group is significantly reduced,comparing to model control group(P0.05).CONCLUSION Seaweed polysaccharide has an inhabitory effect on the rats with IPF induced by BLM." @default.
- W2388960147 created "2016-06-24" @default.
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- W2388960147 date "2008-01-01" @default.
- W2388960147 modified "2023-09-25" @default.
- W2388960147 title "Study on the effect of seaweed polysaccharide on BLM induced interstitial pulmonary fibrosis in rats" @default.
- W2388960147 hasPublicationYear "2008" @default.
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