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- W2389006985 abstract "Objective:To assess the feasibility of three-dimensional(3D) whole-liver perfusion MR imaging for the quantitative analysis of colorectal hepatic metastases(CRHMs).Methods:3D whole-liver perfusion MR imaging was performed in 27 patients with CRHMs using 3D volume-interpolated breath-hold examination(VIBE) sequence,which were obtained during the injection of 0.1 mmol/kg(body weight) of contrast medium at 5 mL/s.The following estimated perfusion parameters were mea-sured with semi-automatic software(Tissue 4D) by two radiologists:the volume transfer constant(Ktrans),the volume of extravascular extracellular space(EES) per volume unit of tissue(Ve),and the flux rate constant between EES and plasma(Kep).Statistical analysis was done using concordance correlation coefficient(CCC) measurements and Bland-Altman plots.Results: The mean differences for inter-observer agreement analysis for the 27 patients with CRHMs were(0.0069±0.0135) min-1 for Ktrans,(-0.0084±0.0371) for Ve,(0.0385±0.0685) min-1 for Kep,respectively;and 95 % limits of agreement were-0.0196 to 0.0333 for Ktrans,-0.0812 to 0.0644 for Ve,-0.0958 to 0.1728 for Kep,respectively.The values of CCC measurements for Ktrans,Ve and Kep were 0.95,0.94 and 0.99,respectively.Conclusions: 3D whole-liver perfusion MR imaging with semi-automatic data analysis is feasible for the quantitative evaluation of the perfusion parameters for CRHMs." @default.
- W2389006985 created "2016-06-24" @default.
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- W2389006985 date "2013-01-01" @default.
- W2389006985 modified "2023-09-26" @default.
- W2389006985 title "Quantitative Study of Three-Dimensional Whole-Liver Perfusion MR Imaging in Patients with Colorectal Hepatic Metastases" @default.
- W2389006985 hasPublicationYear "2013" @default.
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