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- W2389099103 abstract "Objective To study the expression of Survivin and its expression of p53,bcl-2 in nasal NK/T cell lymphomas.Methods Immunohistochemical assay was used to detect the expression of Survivin,p53,bcl-2 genes in 24 nasal NK/T cell lymphoma samples and 17 benign lymph node lesions.Results Survivin was positive in 11 of 24(45.8%) cases of nasal NK/T cell lymphomas,but its expression was detected only in 2 of 17 cases of benign lymph node lesions and concentrated in a few germinal center cells, P0.025.The expression of Survivin gene highly correlated with p53 expression,P0.05,but not bcl-2 expression.Conclusions Apoptosis inhibition by overexpression of Survivin might be involved in the onset and process of nasal NK/T cell lymphoma,independent of or in cooperation with bcl-2 and p53 expression." @default.
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- W2389099103 date "2003-01-01" @default.
- W2389099103 modified "2023-09-23" @default.
- W2389099103 title "Expression of survivin gene and its relationship with expression of p53,bcl-2 gene in nasal NK/T cell lymphmas" @default.
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