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- W2389120264 abstract "Objective To analyze the clinical and pathological characters of lipid storage myopathy,and to investigate the etiology and therapeutic effects.Methods Six cases of lipid storage myopathy diagnosed by muscle biopsies with microscopic and/or electronic microscopic examination were collected in order to analyze the charateristics of the clinical manifestation,EMG,serum creatine kinase and pathological changes by muscle biopsy.Results The main clinical manifestation of this disease was characterized by limbs muscle weakness proximal and sports intolerance.The level of serum creatine kinase most increases and the EMG may appear as chronic myogenic damage and/or myogenic damage.And the typical change of lipid storage can be found by every muscle biopsy.The symptoms of patients got ameliorated after being administrated with drugs,such as vitamin B,neurotrophy drugs,low fat and protein and high carbohydrate diet.Conclusions Current diagnosis of the disease is depended on the clinical manifestations,serum creatine kinase,EMG and muscle biopsy,carnitine content,and the confirmed diagnosis is due up to pathological features of muscle biopsy,and the specific typing can be obtained by biochemistry examination.The combined therapies with corticoid,vitamin and diet abundent of carnitine are effective to attenuate the clinical symptoms,and specific treatments will be given if identified etiological factors are dicovered after biochemistry examination." @default.
- W2389120264 created "2016-06-24" @default.
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- W2389120264 date "2009-01-01" @default.
- W2389120264 modified "2023-09-24" @default.
- W2389120264 title "Clinical and pathological characteis of lipid storage myopathy" @default.
- W2389120264 hasPublicationYear "2009" @default.
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