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- W2389123062 abstract "Objective: To explore the role of rapamycin in the pathogenesis of posterior capsule opacification(PCO).Methods: Twelve New Zealand rabbits(24 eyes) were performed phacoemulsification and randomly divided into 4 groups.The irrigation solution of 7.5?ng/ml,15?ng/ml and 30?ng/ml rapamycin was used in 3 experimental groups respectively.The posterior capsule and cornea were observed with slit-lamp microscope in different times,then 3 months after the rabbits were killed,the histopathological changes and transmission electronic microscope examination were measured.Results: The incidence of PCO was significantly decreased in the 15?ng/ml and 30?ng/ml rapamycin groups compared with the control group in the 12th week after the operation(P0.05).Conclusion: Rapamycin can inhibit the PCO formation without obvious toxicity." @default.
- W2389123062 created "2016-06-24" @default.
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- W2389123062 date "2006-01-01" @default.
- W2389123062 modified "2023-09-25" @default.
- W2389123062 title "Rapamycin inhibits the pathogenesis of posterior capsule opacification: experimental study on rabbit" @default.
- W2389123062 hasPublicationYear "2006" @default.
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