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- W2389144294 abstract "Objective To investigate the changes and roles of cytosolic free calcium concentration (i) in hematoporphyrin monomethyl ether(HMME) photodynamic therapy(HMME PDT) treated HeLa cells Methods The percentages of HeLa cells death and i were respectively measured by MTT methods and fluorospectrophotometry post PDT treatment Simultaneously, Sarco/endoplasmic reticulum calcium ATPase2 (SERCA2) protein degradation in HMME PDT treated HeLa cells was analyzed by Western blotting Results HMME PDT immediately induced i increase in a PDT dose dependent manner, i decreased by BAPTA/AM rescued HeLa cells from death HMME PDT had also caused SERCA2 protein degradation in a PDT dose dependent manner Conclusions i can immediately increase in HeLa cells post HMME PDT i increase, which may correlated to SERCA2 protein degradation caused by HMME PDT, can promote HeLa cell death" @default.
- W2389144294 created "2016-06-24" @default.
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- W2389144294 date "2004-01-01" @default.
- W2389144294 modified "2023-09-24" @default.
- W2389144294 title "Role of Calcium in Hematoporphyrin Monomethyl Ether Photodynamic Therapy Induced HeLa Cells Death" @default.
- W2389144294 hasPublicationYear "2004" @default.
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