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- W2389206932 abstract "Objective To study the left ventricular systolic function in rats with chronic heart failure before and after administration. Methods Twelve control rats, 20 rats with chronic heart failure, 20 orchiectomy rats admitted with adriamycin and 20 orchiectomy (ORX+AR) rats admitted with adriamycin and testosterone (ORX+AR+T) were involved in the study. The left ventricular diameter (LV), the left ventricular end diastolic volume (EDV), fractional shortening (FS) were measured through M mode echocardiography. The longitudinal systolic velocity (Vs) of the two points at the mitral annulus (posteroseptal and lateral wall) was measured by QTVI. Results The LV and EDV of AR and AR+ORX groups were higher than those of the control group ( P 0.05). The FS and Vs were significantly different between ORX+AR rats and ORX+AR+T rats ( P 0.05). Conclusion Testosterone could improve left ventricular systolic function in rats with CHF which testosterone was decreased. QTVI is a new method to assess cardiac function in rats." @default.
- W2389206932 created "2016-06-24" @default.
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- W2389206932 date "2005-01-01" @default.
- W2389206932 modified "2023-09-25" @default.
- W2389206932 title "Effects of testosterone on left ventricular systolic function in rats with chronic heart failure" @default.
- W2389206932 hasPublicationYear "2005" @default.
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