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- W2389215031 abstract "Purpose To investigate histomorphologial and immunophenotypic differences of endometrioid adenocarcinoma of cervix uter and endometrioid adenocarcinoma of corpus uteri.Methods Histomorphologial and immunohistochemical observation were used in the study to compare 8 cases of cervical endometrioid adenocarcinoma and 76 cases of uterine endometrioid adenocarcinoma.Results Cervical endometrioid adenocarcinoma and uterine endometrioid adenocarcinoma of corpus were similar on morphological,but their positive expression rates of markers were vimentin(0,95.45%),CEA(100%,45.45%),p53(12.50%,31.82%),ER(0,54.54%),PR(0,60.61%),Ki-67(75.0%,12.12%),HPV16/18(100%,3.03%),p16(100%,46.97%),and Cam5.2(12.50%,62.12%).There were significant differences between them in the positive rates of vimentin,CEA,ER,PR,p16,Ki-67,HPV16/18,PAS,Cam5.2(P0.05).And no significant differences in positive p53 expression were observed(P0.05).Conclusions The difference of immunologic markers expression,especially including vimentin,CEA,ER,PR,p16,Ki-67,HPV16/18,PAS,and Cam5.2 are a key point for differential diagnosis between endometrioid adenocarcinoma of cervix and uterine endometrioid adenocarcinoma.p53 may be used as an adjunctive immunologic marker in the differential diagnosis." @default.
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- W2389215031 date "2012-01-01" @default.
- W2389215031 modified "2023-09-27" @default.
- W2389215031 title "Clinical pathology and immunohistochemical phenotype analysis of endometrioid adenocarcinoma of cervix uteri and endometrioid adenocarcinoma of corpus uteri" @default.
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