Matches in SemOpenAlex for { <https://semopenalex.org/work/W2389217967> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2389217967 abstract "Objective To study the effects of ethanol extract from Java Brucea Fruit on platelet-derived growth factor receptor β(PDGFRβ) mediated cell migration and to obtain the valuable messages on the characteristics of its active ingredient.Methods PAE cells was transfected with the vector expressing human PDGFRβ with Transfectom 2000;After screening by G418 resisitance,RT-PCR was used to monitor the expression of PDGFRβ in the cells;Wound healing of the cells was used to examine the lowest consistency of PDGFBB and inhibitory effect of ethanol extract of Java Brucea Fruit on cell migration after restoring 24 h.Results Human PDGFRβ was stably expressed in PAE cells transfected with the expressing vector.The lowest consistency of exogenous PDGFBB which promoted PDGFRβ mediated cell migration was 10 μg·L-1.70% ethanol extract of Java Brucea Fruit which strongly inhibited PDGFRβ mediated cell migration was dose-dependent(P0.05),50% and 25% ethanol extract from Java Brucea Fruit(≤10 μg·L-1) had the weaker inhibitory effect,ethanol extract from Java Brucea Fruit(10 μg·L-1) mainly caused the death of the cell.Conclusion Ethanol extract of Java Brucea Fruit has a strongly inhibitory effect on the PDGFRβ mediated cell migration which could play a major role in its effects against metastasis of malignant tumor,the active ingredients of it could be more dissolvable in the 70% ethanol." @default.
- W2389217967 created "2016-06-24" @default.
- W2389217967 creator A5070887372 @default.
- W2389217967 date "2009-01-01" @default.
- W2389217967 modified "2023-09-23" @default.
- W2389217967 title "Inhibitory effect of ethanol extract from Java Brucea Fruit on cell migration mediated by platelet-derived growth factor receptor β" @default.
- W2389217967 hasPublicationYear "2009" @default.
- W2389217967 type Work @default.
- W2389217967 sameAs 2389217967 @default.
- W2389217967 citedByCount "0" @default.
- W2389217967 crossrefType "journal-article" @default.
- W2389217967 hasAuthorship W2389217967A5070887372 @default.
- W2389217967 hasConcept C134018914 @default.
- W2389217967 hasConcept C137738243 @default.
- W2389217967 hasConcept C1491633281 @default.
- W2389217967 hasConcept C170493617 @default.
- W2389217967 hasConcept C17077164 @default.
- W2389217967 hasConcept C180361614 @default.
- W2389217967 hasConcept C185592680 @default.
- W2389217967 hasConcept C2775960820 @default.
- W2389217967 hasConcept C2780161600 @default.
- W2389217967 hasConcept C502942594 @default.
- W2389217967 hasConcept C54355233 @default.
- W2389217967 hasConcept C55493867 @default.
- W2389217967 hasConcept C81885089 @default.
- W2389217967 hasConcept C86803240 @default.
- W2389217967 hasConcept C98274493 @default.
- W2389217967 hasConceptScore W2389217967C134018914 @default.
- W2389217967 hasConceptScore W2389217967C137738243 @default.
- W2389217967 hasConceptScore W2389217967C1491633281 @default.
- W2389217967 hasConceptScore W2389217967C170493617 @default.
- W2389217967 hasConceptScore W2389217967C17077164 @default.
- W2389217967 hasConceptScore W2389217967C180361614 @default.
- W2389217967 hasConceptScore W2389217967C185592680 @default.
- W2389217967 hasConceptScore W2389217967C2775960820 @default.
- W2389217967 hasConceptScore W2389217967C2780161600 @default.
- W2389217967 hasConceptScore W2389217967C502942594 @default.
- W2389217967 hasConceptScore W2389217967C54355233 @default.
- W2389217967 hasConceptScore W2389217967C55493867 @default.
- W2389217967 hasConceptScore W2389217967C81885089 @default.
- W2389217967 hasConceptScore W2389217967C86803240 @default.
- W2389217967 hasConceptScore W2389217967C98274493 @default.
- W2389217967 hasOpenAccess W2389217967 @default.
- W2389217967 hasRelatedWork W2012928718 @default.
- W2389217967 hasRelatedWork W2077566839 @default.
- W2389217967 hasRelatedWork W2130128364 @default.
- W2389217967 hasRelatedWork W2134803695 @default.
- W2389217967 hasRelatedWork W2171353487 @default.
- W2389217967 hasRelatedWork W2280209632 @default.
- W2389217967 hasRelatedWork W2296436019 @default.
- W2389217967 hasRelatedWork W2323475877 @default.
- W2389217967 hasRelatedWork W2367243104 @default.
- W2389217967 hasRelatedWork W2370195364 @default.
- W2389217967 hasRelatedWork W2389086855 @default.
- W2389217967 hasRelatedWork W2583962011 @default.
- W2389217967 hasRelatedWork W2782413479 @default.
- W2389217967 hasRelatedWork W2916037454 @default.
- W2389217967 hasRelatedWork W2997813914 @default.
- W2389217967 hasRelatedWork W3005617091 @default.
- W2389217967 hasRelatedWork W3082807711 @default.
- W2389217967 hasRelatedWork W3181424366 @default.
- W2389217967 hasRelatedWork W2085547834 @default.
- W2389217967 hasRelatedWork W2753091496 @default.
- W2389217967 isParatext "false" @default.
- W2389217967 isRetracted "false" @default.
- W2389217967 magId "2389217967" @default.
- W2389217967 workType "article" @default.