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- W2389244149 abstract "Aim: To establish comparatively simply and rapidly a dementia rat's model by blocking the energy metabolism. Methods: 5% sodium azide 1 μL was injected bilaterally into the CA1 of hippocampus ,3 times in 3 d, 1 times per day; Morris maze test was made on the 3rd day after the final injection,finally morphologic test was made. Results: 1) The average latency and error numbers in model rats increased statistially as compared with the controls (P0.05). 2) The mitochondrion number of hippocampus neuron in model rats reduced obviously, and pyknosis or vacuole appeared in mitochondrion. 3) Nucleus showed colliquation or vacuole-like degeneration etc. Conclusion: The method that injecting sodium azide into the rat's hippocampus can established the energy metabolism block type of dementia rat's model more simply and rapidly ." @default.
- W2389244149 created "2016-06-24" @default.
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- W2389244149 date "2003-01-01" @default.
- W2389244149 modified "2023-09-25" @default.
- W2389244149 title "A dementia rat's model made by blocking the energy metabolism" @default.
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