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- W2389334292 abstract "Objective: To investigate the effects of sterilized methods for anesthetic machine on airway inflammatory response in normal subjects and the patients with chronic obstructive pulmonary disease(COPD) during inhalation anesthesia.Methods: 80 patients undergoing abdominal surgeries and inhalation anesthesia were randomly identified as normal(n=40)or COPD(classⅠ or ⅡA)(n=40)by history-taking and the pulmonary function testing.Both groups of the subjects were randomly divided into group ETHO and group Glutaral,using the anesthetic machine sterilized by ETHO and Glutaral respectively.The patients were intubated with left side double lumen endotracheal tubes.The BAL were sampled at 0,2,4 hour after intubations.The concentrations of cytokines(TNF-α、IL-1β、IL-2、IL-6、IL-8) in bronchoalveolar lavage fluid(BALF) were determined.Results: The levels of both TNF-alpha and IL-1β in BALF were significantly lower at 4h following mechanical ventilation in group CE than those in group CG.Conclusion: The method of ETHO sterilized anesthetic machine shows better in reducing the airway inflammatory response in patients with COPD during inhalation anesthesia than the method of 2% glutaral soak and does the effect of protecting airway." @default.
- W2389334292 created "2016-06-24" @default.
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- W2389334292 date "2007-01-01" @default.
- W2389334292 modified "2023-09-23" @default.
- W2389334292 title "Effect of sterilized methods for anesthetic machine on airway inflammatory response during inhalation anesthesia" @default.
- W2389334292 hasPublicationYear "2007" @default.
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