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- W2389336411 abstract "The ATP-binding cassette sub-family G member 2(ABCG2) protein plays a crucial role on the milking traits of cattle.But its population genetic characteristics and association with milk production in buffalo were unclear.In this study,ABCG2 exon 9 of 466 buffalo sampled from 4 river type and 9 swamp type populations were examined using PCR-SSCP and PCR product direct sequencing techniques.The results revealed that sequences of ABCG2 exon 9 in river type and swamp type buffalo were identical,which consist of 251 nucleotides with no SNP discovered,but one TC substitution(g.SNP44769 TC) was detected in intron 9.Compared with published data of the bovidae species in GenBank database,one GA substitution(c.SNP1018 GA) was found in one river buffalo sequence and lead to the change of the 340th amino acid residues from Valine to Isoleucine(p.V340I) in ABCG2.And the numbers of nucleotide sequence differences among buffalo,cattle,goat and sheep were 5,8,11,respectively,which suggest that there are distinct genetic differences between buffalo and the other bovidae species.The results in the present study indicate that ABCG2 exon 9 has been fixed in buffalo and probably had no direct correlation with the trait of buffalo milk yield." @default.
- W2389336411 created "2016-06-24" @default.
- W2389336411 creator A5049823434 @default.
- W2389336411 date "2012-01-01" @default.
- W2389336411 modified "2023-09-22" @default.
- W2389336411 title "Population Genetic Characteristics Analysis of Exon 9 of ABCG2 Gene in Water Buffalo(Bubalus bubalis)" @default.
- W2389336411 hasPublicationYear "2012" @default.
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